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Nexgard Spectra vs. Advocate: Which One to Go For?

  Jul 01, 2025

Nexgard Spectra vs Advocate

For a dog parent, ensuring that their pet is free from parasites is of utmost importance. The pesky organisms including fleas, ticks, worms, etc. tend to infest canines of all breeds and ages and subject them to infections and diseases. Therefore, it becomes highly important for all dog parents to use efficient parasite control treatments to keep both internal and external parasites at bay.

In this blog, we will shed light on two such parasitic control treatments for dogs, NexGard Spectra and Advocate. We will also help you with a detailed analysis of the two to help you opt for the one that suits your furry baby.

Read on to find out more.

NexGard Spectra vs. Advocate – An Overview

NexGard Spectra

Nexgard Spectra

NexGard Spectra is an oral treatment indicated to prevent heartworm disease caused by Dirofilaria immitis. It also kills fleas, treats and prevents tick infestations and treats and controls mite infestations. The oral chew prevents and controls adult roundworms, hookworms and whipworms. The formula also protects against the development of adult spirocerca lupi in the oesophagus of dogs. It is suitable for dogs and puppies from 8 weeks of age, weighing at least 2kg.

Advocate

Advocate

Advocate is a spot-on treatment that treats and prevents flea infestations, including the larval stages. It also reduces the incidence of Flea Allergy Dermatitis and prevents heartworm disease caused by Dirofilaria immitis. The formula also treats gastrointestinal worms like roundworms, hookworms and whipworms. This topical composition treats biting lice, ear mite infestation and demodicosis. It also treats and reduces circulating microfilariae, prevents angiostrongylosis, treats French heartworms and fox lungworms, prevents spirocercosis (Spirocerca lupi) and treats sarcoptic mange and eye worms. Advocate is formulated for dogs and puppies from 7 weeks of age.

NexGard Spectra & Advocate – Similarities & Differences

Let’s look at the key similarities and differences between NexGard Spectra and Advocate:

Similarities:

  • Both NexGard Spectra and Advocate are indicated to kill fleas and treat and prevent flea infestations.
  • Both treatments protect dogs against heartworm disease.
  • Each of them treats and controls gastrointestinal worms like roundworms, hookworms and whipworms.
  • Both treatments kill mange and mites.
  • NexGard Spectra & Advocate protect dogs against Spirocerca lupi.

Differences:

  • While NexGard Spectra is an oral chew, Advocate is a spot-on treatment.
  • NexGard Spectra treats and prevents tick infestations. However, Advocate is not effective against ticks.
  • NexGard Spectra is suitable for dogs and puppies from 8 weeks of age. Advocate, on the other hand, is formulated for canines from 7 weeks of age.
  • NexGard Spectra features Afoxolaner and Milbemycin Oxime as its active ingredients. Advocate is composed of Imidacloprid and Moxidectin.
  • Advocate protects dogs against angiostrongylosis, French heartworms, fox lungworms, and eye worms. NexGard Spectra is not known to be effective against these conditions.

Comparative Analysis

The following table provides a comparison of the key features of NexGard Spectra and Advocate:

NexGard Spectra vs. Advocate

Concluding Note

Both NexGard Spectra and Advocate are vet-recommended treatments that protect dogs against a wide range of internal and external parasites. However, they have different parasite coverage, composition and age criteria.

If you want to protect your canine against fleas, intestinal worms like roundworms, hookworms and whipworms, heartworm disease, mange and mites as well as Spirocerca lupi, you can go for either of the treatments. However, if you want to address tick infestations, you should administer NexGard Spectra. Also, if you are looking for coverage against generalised demoticosis, lice, angiostrongylosis, French heartworms, fox lungworms and eye worms, you will need to opt for Advocate. Always make sure your furry companion meets the age and weight requirements mentioned on the product label.

You can purchase both NexGard Spectra and Advocate at the best prices from BudgetPetSupplies. Check out our online store today to enjoy lucrative deals on a wide array of pet treatments and essentials from the comfort of your home.

Nexgard Spectra vs Advocate

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